5/16/2023 0 Comments Geodist bioinformatics 2016![]() Understanding a species’ genome-wide nucleotide diversity requires information about historical conditions (e.g. Our whole-genome study provides insights into the evolution of one of the most reduced eukaryotic genomes and shows how different processes shape genomic diversity of an obligate parasite. We identified several genetic regions under potential selection. ![]() colligata phylogeny and thus estimate its mutation rate. The co-phylogeography allowed us to calibrate the O. magna predominantly found in warmer areas. colligata exhibits adaptations to colder habitats, which differentiates it from other microsporidian gut parasites of D. The observed geographic distribution reflects previous findings that O. colligata and its host highlighting the long-term, intimate relationship between them. We found an overlapping phylogeography between O. colligata is specific to the freshwater crustacean Daphnia magna and has one of the smallest known eukaryotic genomes. ![]() Although very closely related microsporidia cause diseases in humans, O. We used genomic samples from 10 populations of the microsporidian parasite Ordospora colligata to investigate present genomic diversity and how it was shaped by evolutionary processes, specifically, the role of phylogeography, co-phylogeography (with the host), natural selection, and transmission mode. In parasites, the mode of transmission and the interactions with the host might supersede the effects of these aspects in shaping parasite genomic diversity. This diversity can inform us about the species’ past and present evolutionary dynamics. The determinants of variation in a species’ genome-wide nucleotide diversity include historical, environmental, and stochastic aspects.
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